Weight Loss
Tirzepatide
May help calm hunger and support a healthier metabolism.
How it works
Tirzepatide
At a glance
- Same active ingredient as Mounjaro® and Zepbound®, prescribed by a US-licensed physician after an online health review
- The most effective weight-loss medication tested in large trials to date: up to 22.5% average body-weight loss (72 weeks, brand-name product)
- Dual-hormone action (GLP-1 + GIP) in a once-weekly injection, starting at a low dose and increasing gradually
- Compounded with glycine or niacinamide based on your individual prescription, with every batch tested by an independent third-party lab
- Medical supervision included for the length of your treatment
What it is
Tirzepatide is the newest generation of weight-loss medication and the most effective one tested in large trials to date. It is the active ingredient in Mounjaro® and Zepbound®. Where semaglutide mimics one gut hormone (GLP-1), tirzepatide mimics two: GLP-1 and GIP. That dual action is why it is often described as a step beyond the first GLP-1 drugs. Ours is a compounded version prepared by a licensed US compounding pharmacy, formulated with either glycine or niacinamide depending on your individual prescription, and prescribed only after a licensed clinician reviews your intake.
How it works
GLP-1 and GIP are hormones your gut releases after eating. Together they regulate appetite, digestion speed, and how your body handles sugar and fat. Supplementing both at once quiets appetite signals in the brain, slows stomach emptying so you stay full longer, and improves insulin response. GIP also acts on receptors in fat tissue involved in energy metabolism, and in practice many patients report fewer digestive side effects on tirzepatide than on GLP-1-only medications. It is a once-weekly injection, started low and increased gradually.
What the research shows
The largest study, a clinical trial called SURMOUNT-1 published in the New England Journal of Medicine, followed 2,539 adults with obesity or overweight who took tirzepatide or placebo for 72 weeks. At the highest dose, participants lost 22.5% of their body weight on average, versus 2.4% on placebo. Nine in ten lost at least 5% of their body weight, and 63% lost 20% or more. In the first large head-to-head trial against semaglutide (SURMOUNT-5, 2025), tirzepatide produced 20.2% average weight loss versus 13.7% for semaglutide over 72 weeks. These trials used the FDA-approved brand-name product; compounded tirzepatide itself has not been through clinical trials.
What to expect
Appetite typically drops noticeably within the first few weeks. Meaningful weight loss builds over months as your dose steps up, and the trial results above reflect about 17 months of treatment. Plan for this as a sustained program, paired with enough protein and regular strength training to protect muscle. After checkout, a licensed clinician reviews your intake before anything ships, and nothing is fulfilled without that review.
Side effects and who it's not for
The most common side effects are digestive: nausea (around 1 in 3 at higher doses in the SURMOUNT-1 trial), diarrhea, constipation, and vomiting, generally mild to moderate and concentrated around dose increases. Rare but serious risks include pancreatitis and gallbladder disease. Tirzepatide is not for you if you are pregnant, planning pregnancy, or have a personal or family history of medullary thyroid cancer or MEN 2. Your clinician screens for all of this during review.
FAQ
Is this the same as Mounjaro® or Zepbound®?
Same active ingredient, tirzepatide. Mounjaro® and Zepbound® are the brand-name FDA-approved products. Ours is prepared by a licensed US compounding pharmacy, formulated with either glycine or niacinamide depending on your prescription. Compounded medications are not FDA-approved, and the FDA does not verify their safety, effectiveness, or quality. That is exactly why we built our own quality chain: we work with a network of US-licensed physicians and a US compounding pharmacy, and every batch is tested by an independent third-party lab to confirm it meets the highest quality standards.
Why glycine or niacinamide, and which one will I get?
Your prescription is personalized: based on your intake, your clinician prescribes tirzepatide compounded with either glycine or niacinamide. Pricing is the same for both. Glycine is an amino acid your body uses to build muscle tissue and collagen and to regulate sleep, and early research suggests it may help protect lean muscle while you eat less; in the vial, it also plays a practical role in keeping the peptide formulation stable. Niacinamide is a form of vitamin B3 that your cells convert into NAD+, a molecule central to energy production, which is why it is paired with a medication that reduces how much you eat. To be clear about the evidence: these combinations themselves have not been through clinical trials. The weight loss comes from the tirzepatide; the addition is a supportive ingredient chosen for you.
Why is it more expensive than some offers I see online?
Because you are not just buying a vial. Your treatment includes a consultation with a highly educated US-licensed physician, ongoing medical supervision for the length of your treatment, and medication from a US compounding pharmacy whose batches are third-party tested. The internet is full of gray-zone offers where you do not know what is in the vial, how it was stored, or whether it contains any active ingredient at all. We deliberately built a premium offering to cut through that: verified medication, real doctors, and supervision included in the price.
Does insurance cover this?
No. In our telehealth setup, insurance coverage is unfortunately not possible, so you pay for your treatment directly. What you get in return is the complete service: your physician consultation, ongoing medical supervision, and third-party tested medication are all included in the price, and longer plans reduce the monthly cost.
Tirzepatide or semaglutide: which is right for me?
In the head-to-head trial, tirzepatide produced greater average weight loss. Semaglutide has a longer track record and, for now, the strongest cardiovascular outcome data. Cost, tolerability, and your health history all matter, and your clinician will help you choose. Neither is wrong; they are different tools.
How fast will I lose weight?
Trial participants at effective doses averaged roughly 1 to 2 pounds per week over the full study period, with the fastest loss usually mid-program. Individual variation is large.
Do I need to diet and exercise?
Yes, in one specific sense: studies show a meaningful share of weight lost on these medications can be lean muscle unless you eat enough protein and do resistance training. The medication handles appetite; you handle what fills the smaller plate.
What happens if I stop?
Our protocols are built so you can eventually stand on your own. Alongside the medication, your treatment includes lifestyle changes designed to make your results stick:
- changes in your diet
- high protein intake
- strength training
- cardio
With those habits in place, maintaining your new weight is realistic. When the time comes, your clinician helps you decide between long-term use, a lower maintenance dose, or tapering off.
All trademarks are the property of their respective owners. This product is not affiliated with, endorsed by, or sponsored by the makers of the brand-name medications referenced above.
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Clinician guided
Every protocol is reviewed by a licensed provider before fulfillment.
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Discreet delivery
Medications ship in plain packaging with free expedited options where available.
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Ongoing care
Stay supported with check-ins, dosage guidance, and care team messaging.